Characterization of a functional V1B vasopressin receptor in the male rat kidney: evidence for cross talk between V1B and V2 receptor signaling pathways

نویسندگان

چکیده

Although V 1B R mRNA has been detected in the kidney, precise renal localization as well pharmacological and physiological properties of this receptor remain unknown. Using original pharmaceutical tools, study brings new data on signaling pathways R, highlights a cross talk between 2 (V R) inner medullary collecting duct, suggests that may counterbalance some pathophysiological conditions antidiuretic effect triggered by activation.

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ژورنال

عنوان ژورنال: American Journal of Physiology-renal Physiology

سال: 2021

ISSN: ['1522-1466', '1931-857X']

DOI: https://doi.org/10.1152/ajprenal.00081.2021